Provides tools for estimating uncertainty in individual polygenic risk scores (PRSs) using both sampling-based and analytical methods, as well as the Best Linear Unbiased Estimator (BLUE). These methods quantify variability in PRS estimates for both binary and quantitative traits. See Henderson (1975) <doi:10.2307/2529430> for more details.
Version: | 1.0.0 |
Depends: | R (≥ 2.10) |
Imports: | data.table, bigstatsr, logistf, stats, utils |
Published: | 2025-09-10 |
Author: | Dovini Jayasinghe [aut, cre, cph], Hong Lee [aut, cph] |
Maintainer: | Dovini Jayasinghe <dovini.jayasinghe at mymail.unisa.edu.au> |
License: | GPL-3 |
URL: | https://github.com/DoviniJ/iPRSue |
NeedsCompilation: | no |
CRAN checks: | iPRSue results |
Reference manual: | iPRSue.html , iPRSue.pdf |
Package source: | iPRSue_1.0.0.tar.gz |
Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
macOS binaries: | r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available |
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