Provides tools for estimating uncertainty in individual polygenic risk scores (PRSs) using both sampling-based and analytical methods, as well as the Best Linear Unbiased Estimator (BLUE). These methods quantify variability in PRS estimates for both binary and quantitative traits. See Henderson (1975) <doi:10.2307/2529430> for more details.
| Version: | 1.0.0 |
| Depends: | R (≥ 2.10) |
| Imports: | data.table, bigstatsr, logistf, stats, utils |
| Published: | 2025-09-10 |
| DOI: | 10.32614/CRAN.package.iPRSue |
| Author: | Dovini Jayasinghe [aut, cre, cph], Hong Lee [aut, cph] |
| Maintainer: | Dovini Jayasinghe <dovini.jayasinghe at mymail.unisa.edu.au> |
| License: | GPL-3 |
| URL: | https://github.com/DoviniJ/iPRSue |
| NeedsCompilation: | no |
| CRAN checks: | iPRSue results |
| Reference manual: | iPRSue.html , iPRSue.pdf |
| Package source: | iPRSue_1.0.0.tar.gz |
| Windows binaries: | r-devel: iPRSue_1.0.0.zip, r-release: iPRSue_1.0.0.zip, r-oldrel: iPRSue_1.0.0.zip |
| macOS binaries: | r-release (arm64): iPRSue_1.0.0.tgz, r-oldrel (arm64): iPRSue_1.0.0.tgz, r-release (x86_64): iPRSue_1.0.0.tgz, r-oldrel (x86_64): iPRSue_1.0.0.tgz |
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