HIMA: High-Dimensional Mediation Analysis

Allows to estimate and test high-dimensional mediation effects based on advanced mediator screening and penalized regression techniques. Methods used in the package refer to Zhang H, Zheng Y, Hou L, Liu L, HIMA: An R Package for High-Dimensional Mediation Analysis. Journal of Data Science. (2025). <doi:10.6339/25-JDS1192>.

Version: 2.3.3
Depends: R (≥ 3.5), ncvreg, glmnet
Imports: utils, stats, MASS, survival, nlme, HDMT, hdi, conquer, quantreg, hommel, iterators, parallel, foreach, doParallel
Suggests: knitr, rmarkdown, testthat
Published: 2025-11-17
DOI: 10.32614/CRAN.package.HIMA
Author: Yinan Zheng ORCID iD [aut, cre], Haixiang Zhang [aut], Lifang Hou [aut], Lei Liu [aut, cph]
Maintainer: Yinan Zheng <y-zheng at northwestern.edu>
BugReports: https://github.com/YinanZheng/HIMA/issues/
License: GPL-3
URL: https://github.com/YinanZheng/HIMA/
NeedsCompilation: no
Citation: HIMA citation info
Materials: README, NEWS
In views: Epidemiology
CRAN checks: HIMA results

Documentation:

Reference manual: HIMA.html , HIMA.pdf
Vignettes: High-Dimensional Mediation Analysis (source, R code)

Downloads:

Package source: HIMA_2.3.3.tar.gz
Windows binaries: r-devel: HIMA_2.3.2.zip, r-release: HIMA_2.3.2.zip, r-oldrel: HIMA_2.3.2.zip
macOS binaries: r-release (arm64): HIMA_2.3.2.tgz, r-oldrel (arm64): HIMA_2.3.2.tgz, r-release (x86_64): HIMA_2.3.2.tgz, r-oldrel (x86_64): HIMA_2.3.2.tgz
Old sources: HIMA archive

Linking:

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