SCORPION: Single Cell Oriented Reconstruction of PANDA Individually Optimized Networks

Constructs cell-type–specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor–target regulatory relationships. It also provides statistical methods for differential edge analysis.

Version: 1.3.2
Depends: R (≥ 3.5.0)
Imports: cli, methods, irlba, igraph, RANN, Matrix, pbapply, dplyr, furrr, future
Suggests: RhpcBLASctl, testthat
Published: 2026-03-10
DOI: 10.32614/CRAN.package.SCORPION
Author: Daniel Osorio ORCID iD [aut, cre], Marieke L. Kuijjer ORCID iD [aut]
Maintainer: Daniel Osorio <daniecos at uio.no>
BugReports: https://github.com/kuijjerlab/SCORPION/issues
License: GPL-3
URL: https://github.com/kuijjerlab/SCORPION
NeedsCompilation: no
CRAN checks: SCORPION results

Documentation:

Reference manual: SCORPION.html , SCORPION.pdf

Downloads:

Package source: SCORPION_1.3.2.tar.gz
Windows binaries: r-devel: SCORPION_1.3.1.zip, r-release: SCORPION_1.3.2.zip, r-oldrel: SCORPION_1.3.2.zip
macOS binaries: r-release (arm64): SCORPION_1.3.2.tgz, r-oldrel (arm64): SCORPION_1.3.2.tgz, r-release (x86_64): SCORPION_1.3.2.tgz, r-oldrel (x86_64): SCORPION_1.3.2.tgz
Old sources: SCORPION archive

Linking:

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